姓名：胡沁沁    职称：副研究员     硕士生导师

入选“2024年上海市东方英才计划青年项目”

办公室地址：上海市黄浦区重庆南路280号1号楼411室

办公室电话：021-63846590转776975

邮箱：qinqinhu@sjtu.edu.cn

教育经历（从本科开始）

2007年-2011年 陕西师范大学 食品科学与工程专业学士

2011年-2016年 浙江大学 生物系统工程专业博士 导师：李延斌

2014年-2016年 美国阿肯色大学 农业与生物系统工程系 联合培养

工作经历

2016年-2019年 复旦大学生物医学研究院，博士后 合作导师：顾宏周

2019年-2021年 复旦大学生物医学研究院，助理研究员

2021年-2021年 上海交通大学医学院全球健康学院，助理研究员

2022年-至今  上海交通大学医学院全球健康学院，副研究员

社会/学术任职和活动

Science in One Health 青年编委

Scientific Reports编委

Sensors期刊客座编辑

科研方向/主要研究内容

功能核酸与生物传感在疾病诊断、食品安全的基础及应用研究：

聚焦食源性风险因素现场监测和重大疾病快速诊断，开发新型分子诊断/生物传感检测方法，筛选功能核酸用于识别与鉴定疾病相关分子

科研项目

发表论文（格式：国标GB／T7714-2015）

1. Qinqin Hu#, Zongxuan Tong#, Ayimukedisi Yalikong#, Li-Ping Ge#,Qiang Shi, Xinyu Du, Pu Wang, Xi-Yu Liu, Wuqiang Zhan, Xia Gao, Di Sun, Tong Fu, Dan Ye, Jie Liu, Chunhai Fan, Yun-Shi Zhong*, Yi-Zhou Jiang*, Hongzhou Gu*. DNAzyme-Based Faithful Probing-and-Pulldown to Identify Candidate Biomarkers of Low Abundance. Nature Chemistry 2024, 16: 122-131.

2. Huimin Li, Leshan Xiu, Xiaokui Guo, Qinqin Hu*, Kun Yin*. Spatiotemporal dual-dimensional separation enables ultra-simple one-pot CRISPR-based molecular diagnostics, Chemical Engineering Journal, 2024, 482: 148872.

3. Fumin Chen, Chenang Lyu, Zhao Li, Leshan Xiu, Huimin Li, Yi Xie, Runzhen Cao, Qinqin Hu*, Kun Yin*. Fully Integrated Microfluidic Platform for Multiplexed Detection of Hunov by a Dynamic Confine-Space-Implemented One-Pot Rpa-Lamp System, Advanced Science, 2023, 2306612.

4. Si-Yu Gu, Fu-Min Chen, Chen-Sheng Zhang, Yi-Bin Zhou, Tian-Yun Li, Ne Qiang, Xiao-Xi Zhang, Jing-Shu Liu, Shu-Xun Wang, Xue-Chen Yang, Xiao-Kui Guo, Qin-Qin Hu*, Xiao-Bei Deng*, Le-Fei Han*. Assessing food security performance from the One Health concept: an evaluation tool based on the Global One Health Index. Infectious Diseases of Poverty, 2023, 12, 88.

5. Yawen He, Qinqin Hu, Samantha San, Tom Kasputis, Maria Gabriella Duarte Splinter, Kun Yin*, Juhong Chen*. CRISPR-based biosensors for human health: A novel strategy to detect emerging infectious diseases. TrAC Trends in Analytical Chemistry 2023, 168, 117342.

6. Fumin Chen#, Qinqin Hu#, Huimin Li, Yi Xie, Leshan Xiu, Yuqian Zhang, Xiaokui Guo*, Kun Yin*. Multiplex Detection of Infectious Diseases on Microfluidic Platforms. Biosensors, 2023, 13, 410.

7. Huimin Li#, Yi Xie#, Fumin Chen, Huiwen Bai, Leshan Xiu, Xiaonong Zhou, Xiaokui Guo*, Qinqin Hu*, Kun Yin*. Amplification-free CRISPR/Cas Detection Technology: Challenges, Strategies, and Perspectives. Chemical Society Reviews 2023, 52(1):361-382.

8. Qinqin Hu#; Zheyan Fang#; Junbo Ge*; Hua Li*. Nanotechnology for Cardiovascular Diseases. The Innovation 2022, 3(2): 100214.

9. Qinqin Hu#; Hua Li#; Lihua Wang; Hongzhou Gu*; Chunhai Fan*. “DNA Nanotechnology Enabled Drug Delivery systems.” Chemical Reviews. 2019, 119(10): 6459-6506.

10. Qinqin Hu#; Sheng Wang; Lihua Wang; Hongzhou Gu*; Chunhai Fan*. DNA Nanostructure-Based Systems for Intelligent Delivery of Therapeutic Oligonucleotides. Advanced Healthcare Materials. 2018, 7, 1-19.

11. Qinqin Hu#; Ronghui Wang; Hong Wang; Michael F. Slavik; Yanbin Li*. “Selection of Acrylamide-Specific Aptamers by a Quartz Crystal Microbalance Combined SELEX Method and Their Application in Rapid and Specific Detection of Acrylamide.” Sensors and Actuators B: Chemical 2018, 273, 220-227.

12. Qinqin Hu#; Yingchun Fu; Xiahong Xu; Zhaohui Qiao; Ronghui Wang;Ying Zhang; Yanbin Li*. “A Colorimetric Detection of Acrylamide in Potato Chips Based on Nucleohile-Initiated Thiol-Ene Michael Addition.” Analyst 2016, 141, 1136-1143.

13. Qinqin Hu#; Xiahong Xu; Yingchun Fu; Yanbin Li*. “Rapid methods for Detecting Acrylamide in Thermally Processed Foods: A Review.” Food Control 2015, 56, 135-146.

14. Qinqin Hu#; Xiahong Xu; Zhanming Li; Ying Zhang; Jianping Wang; Yingchun Fu; Yanbin Li*. “Detection of Acrylamide in Potato Chips Using a Fluorescent Sensing Method Based on Acrylamide Polymerization-Induced Distance Increase Between Quantum Dots.” Biosensors and Bioelectronics 2014, 54, 64-71.

15. Qinqin Hu#; Xiahong Xu; Zhanming Li; Ying Zhang; Yanbin Li*. “Rapid Detection of Acrylamide in Food Using a Fluorescent Sensing Method Based on Functional CdSe/ZnS Quantum Dots.” IEEE Sensors 2013, 414-417.

16. Yi Xie, Huimin Li, Fumin Chen, Srisruthi Udayakumar, Khyati Arora, Hui Chen, Yang Lan, Qinqin Hu, Xiaonong Zhou, Xiaokui Guo*, Leshan Xiu*, and Kun Yin*. Clustered Regularly Interspaced short palindromic repeats-Based Microfluidic System in Infectious Diseases Diagnosis: Current Status, Challenges, and Perspectives. Advanced Science 2022, 2204172.

17. Zongxuan#, Tong; Qinqin Hu; Hongzhou Gu*. “Deoxyribozymes: Selection, Biosensing and Outlook.” Chemical Journal of Chinese Universities-Chinese 2020, 41 (11), 2345-2355.

18. Hong Wang#*; Lijun Wang; Qinqin Hu; Ronghui Wang; Yanbin Li; Michael Kidd. “Rapid and Sensitive Detection of Campylobacter jejuni in Poultry Products Using a Nanoparticle-Based Piezoelectric Immunosensor Integrated with Magnetic Immunoseparation.” Journal of Food Protection 2018, 81 (8), 1321–1330.

19. Zhuo Zhao#; Lizhou Xu; Qinqin Hu; Ronghui Wang; Hong Wang; Yanbin Li*. “A portable and automatic biosensing instrument for simultaneous detection of foodborne pathogens using nanobead-based magnetic separation and quantum dot-labeled fluorescent measurement.” 2016 ASABE Annual International Meeting 162461406. (doi:10.13031/aim.20162461406)

20. Huiyan Li#; Fangfei Yin; Xinyi Li; Wannan Jia; Jia Ding; Li Zhang; Zhonghua Wang; Qinqin Hu; Jieliang Zuo; Huliang Jia; Li hua Wang; Chunhai Fan*; Hongzhou Gu*; Jian Wu.* “Novel aptasensor-based assay of sonic hedgehog ligand for detection of portal vein invasion of hepatocellular carcinoma” Biosensors and Bioelectronics 2021, 174, 112738.

英文：

Name：Qinqin Hu

Degree：Ph.D.

Title：Associate Researcher/Professor

Email Address: qinqinhu@sjtu.edu.cn

Office Address: Rm 412, Building 1, 280 South Chongqing Road, Shanghai

Office Tel: 021-63846590 * 776974

Education：

2007-2011, B.D.  Shaanxi Normal University (Food science and technology).

2011-2016, Ph.D.  Zhejiang University, Biosystem engineering, supervisor: Prof. Yanbin Li.

2014-2016, Joint Ph.D. student, University of Arkansas (Agricultural and biological system engineering, CSC funding)

Appointments：

2016-2019, Institutes of Biomedicine, Fudan University, Postdoc training, supervisor: Prof. Hongzhou Gu

2019-2021, Institutes of Biomedicine, Fudan University, Assistant Researcher

2021-2021, Shanghai Jiao Tong University School of Medicine, Assistant Researcher

2022-Present, Shanghai Jiao Tong University School of Medicine, Associate Researcher/Professor

Academic Participation and Activities：

Guest Editor of Sensors

Editor of Science in One Health

Research Interest：

Dr. Qinqin Hu is interested in the basic and application research on developing biosensors and functional nucleic acids for disease diagnostic and food safety. She especially focuses on 1) novel molecular diagnostic techniques (CRISPR/Cas-based) and nano/optical biosensors for food hazards surveillance and rapid disease diagnosis; 2) In vitro selection of functional nucleic acids including DNAzymes or aptamers for the identification of potential disease-related molecules.