王兆军 教授 博士生导师

上海交通大学医学院全球健康学院 副院长

上海交通大学医学院党委教师工作部 副部长

上海交通大学基础医学院 课程组长

上海市免疫学研究所 课题组长

 

联系方式

办公室：上海市重庆南路280号西区5号楼1207室，邮编200025

电话：021-63846590（x776349）

邮箱：zjwang@sjtu.edu.cn

 

教育经历

2006/6 上海交通大学，博士

2002/6 上海第二医科大学，硕士

1996/6 上海第二医科大学，学士

工作经历

2023/2-至今         上海交通大学全球健康学院，副院长

2021/5-至今         上海市免疫学研究所，课题组长

2017/7-至今         上海交通大学医学院，党委教师工作部，副部长

2014/12-至今        上海交通大学医学院，免疫学与微生物学系，教授

2008/11-2012/6     [美国]宾夕法尼亚大学医学院，博士后研究人员

2006/12-2014/12     上海交通大学医学院，副教授

2003/1-2006/12       上海第二医科大学（现上海交通大学医学院），讲师

1996/7-2002/12     上海第二医科大学，助教

 

研究方向

长期致力于感染免疫研究，尤其是热带病与炎症微环境中天然免疫细胞的功能调控方面，取得了一系列原创性科学发现。主持国家自然基金项目6项、教育部与省部级课题8项，在Nature Immunology、Nature communication、 Journal of Clinical Investigation、PNAS、Cell death and differentiation、PLoS Neglected Tropical Diseases、Frontiers in Immunology等高水平杂志上发表第一或通讯作者论文30余篇。研究成果曾获全国百篇优秀博士论文。个人曾获中国免疫学青年学者奖、宝钢优秀教师奖，入选东方英才拔尖项目、上海市浦江人才等。

代表性研究论文

[1] DU X, REN B, LI C, et al. PRL2 regulates neutrophil extracellular trap formation which contributes to severe malaria and acute lung injury [J]. Nature communications, 2024, 15(1).

[2] LEI Y, GUO X, LUO Y, et al. Synovial microenvironment-influenced mast cells promote the progression of rheumatoid arthritis [J]. Nature communications, 2024, 15(1).

[3] SUN Z-S, WAN E-Y, AGBANA Y L, et al. Global One Health index for zoonoses: A performance assessment in 160 countries and territories [J]. iScience, 2024.

[4] LI Q, YUE T, DU X, et al. HSC70 mediated autophagic degradation of oxidized PRL2 is responsible for osteoclastogenesis and inflammatory bone destruction [J]. Cell Death & Differentiation, 2023, 30(3): 647-59.

[5] ZHANG X-X, LI X-C, ZHANG Q-Y, et al. Tackling global health security by building an academic community for One Health action [J]. Infectious Diseases of Poverty, 2023, 12(1).

[6] LI Q, LI X, KAN S, et al. Clonorchis sinensis calcium-binding protein Cs16 causes acute hepatic injury possibly by reprogramming the metabolic pathway of bone marrow-derived monocytes [J]. Frontiers in Cellular and Infection Microbiology, 2023, 13.

[7] KAN S, LI Q, LI H-M, et al. Clonorchis sinensis infection modulates key cytokines for essential immune response impacted by sex [J]. PLoS neglected tropical diseases, 2022, 16(9).

[8] WU C, DU X, TANG L, et al. Schistosoma japonicum SjE16.7 Protein Promotes Tumor Development via the Receptor for Advanced Glycation End Products (RAGE) [J]. Frontiers in immunology, 2020, 11.

[9] DU X, ZHANG Y, LI X, et al. PRL2 serves as a negative regulator in cell adaptation to oxidative stress [J]. Cell & bioscience, 2019, 9(1).

[10] YIN C, WU C, DU X, et al. PRL2 Controls Phagocyte Bactericidal Activity by Sensing and Regulating ROS [J]. Frontiers in immunology, 2018, 9.

[11] FAYNGERTS S A, WANG Z, ZAMANI A, et al. Direction of leukocyte polarization and migration by the phosphoinositide-transfer protein TIPE2 [J]. Nature immunology, 2017, 18(12): 1353-60.

[12] FANG Y, WU C, CHEN Q, et al. SjE16.7 activates macrophages and promotes Schistosoma japonicum egg-induced granuloma development [J]. Acta tropica, 2015, 149: 49-58.

[13] WANG Z, FAYNGERTS S, WANG P, et al. TIPE2 protein serves as a negative regulator of phagocytosis and oxidative burst during infection [J]. Proceedings of the National Academy of Sciences, 2012, 109(38): 15413-8.

[14] WANG Z, QIU J, GUO T B, et al. Anti-Inflammatory Properties and Regulatory Mechanism of a Novel Derivative of Artemisinin in Experimental Autoimmune Encephalomyelitis [J]. The Journal of Immunology, 2007, 179(9): 5958-65.

[15] HU W, YAN Q, SHEN D-K, et al. Evolutionary and biomedical implications of a Schistosoma japonicum complementary DNA resource [J]. Nature genetics, 2003, 35(2): 139-47.

 

 

 

 

 

 

 

 

英文：

Name：Zhaojun Wang                

Title：Professor, Doctoral Supervisor

Deputy Dean, School of Global Health, Shanghai Jiao Tong University School of Medicine
Deputy Director, Department of Teachers' Work of the Party Committee, Shanghai Jiao Tong University School of Medicine

Course leader, School of Basic Medicine, Shanghai Jiao Tong University
PI, Shanghai Institute of Immunology

 

Contact Methods:

Office Address: 280 South Chongqing Road, Room 1207

Office Tel:021-63846590 (x776349)

Email Address: zjwang@sjtu.edu.cn

Education：

Ph.D in Immunology, Shanghai Jiao Tong University, China

Master in Microbiology and Parasitology, Shanghai Second Medical University, China

Bachelor in Medical laboratory science, Shanghai Second Medical University, China

Appointments:

2023/2-present           Deputy Dean, School of Global Health, Shanghai Jiao Tong University
2021/5-now                 PI, Shanghai Institute of Immunology
2017/7-present           Deputy director, Department of Teachers' work of the party committee, Shanghai Jiao Tong University School of Medicine
2014/12-present         Professor, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine
2008/11-2012/6          [USA] Postdoctoral researcher, University of Pennsylvania School of Medicine
12/2006-12/2014        Associate Professor, Shanghai Jiao Tong University School of Medicine

2003/1-2006/12          Lecturer, Shanghai Second Medical University (now Shanghai Jiao Tong University School of Medicine)
1996/7-2002/12          Assistant Professor, Shanghai Second Medical University

 

Research Direction:

Prof. Wang has been committed to infection immunity research for a long time, especially in the functional regulation of natural immune cells in tropical diseases and inflammatory microenvironments, and has made a series of original scientific discoveries. Presided over 6 National Natural Fund projects, 8 projects of the Ministry of Education and provincial and ministerial level, In Nature Immunology, Nature communication, Journal of Clinical Investigation, PNAS, Cell death and differentiation, PLoS Neglected Tropical Diseases, Frontiers in Immunology and other high-level journals published more than 30 first or corresponding author papers. His research results have been awarded one hundred outstanding doctoral dissertations nationwide. He has won the China Immunology Young Scholar Award, Baosteel Excellent Teacher Award, selected as the Oriental Outstanding Talent Project, Shanghai Pujiang Talent and so on.

Representative Publications:

[1] DU X, REN B, LI C, et al. PRL2 regulates neutrophil extracellular trap formation which contributes to severe malaria and acute lung injury [J]. Nature communications, 2024, 15(1).

[2] LEI Y, GUO X, LUO Y, et al. Synovial microenvironment-influenced mast cells promote the progression of rheumatoid arthritis [J]. Nature communications, 2024, 15(1).

[3] SUN Z-S, WAN E-Y, AGBANA Y L, et al. Global One Health index for zoonoses: A performance assessment in 160 countries and territories [J]. iScience, 2024.

[4] LI Q, YUE T, DU X, et al. HSC70 mediated autophagic degradation of oxidized PRL2 is responsible for osteoclastogenesis and inflammatory bone destruction [J]. Cell Death & Differentiation, 2023, 30(3): 647-59.

[5] ZHANG X-X, LI X-C, ZHANG Q-Y, et al. Tackling global health security by building an academic community for One Health action [J]. Infectious Diseases of Poverty, 2023, 12(1).

[6] LI Q, LI X, KAN S, et al. Clonorchis sinensis calcium-binding protein Cs16 causes acute hepatic injury possibly by reprogramming the metabolic pathway of bone marrow-derived monocytes [J]. Frontiers in Cellular and Infection Microbiology, 2023, 13.

[7] KAN S, LI Q, LI H-M, et al. Clonorchis sinensis infection modulates key cytokines for essential immune response impacted by sex [J]. PLoS neglected tropical diseases, 2022, 16(9).

[8] WU C, DU X, TANG L, et al. Schistosoma japonicum SjE16.7 Protein Promotes Tumor Development via the Receptor for Advanced Glycation End Products (RAGE) [J]. Frontiers in immunology, 2020, 11.

[9] DU X, ZHANG Y, LI X, et al. PRL2 serves as a negative regulator in cell adaptation to oxidative stress [J]. Cell & bioscience, 2019, 9(1).

[10] YIN C, WU C, DU X, et al. PRL2 Controls Phagocyte Bactericidal Activity by Sensing and Regulating ROS [J]. Frontiers in immunology, 2018, 9.

[11] FAYNGERTS S A, WANG Z, ZAMANI A, et al. Direction of leukocyte polarization and migration by the phosphoinositide-transfer protein TIPE2 [J]. Nature immunology, 2017, 18(12): 1353-60.

[12] FANG Y, WU C, CHEN Q, et al. SjE16.7 activates macrophages and promotes Schistosoma japonicum egg-induced granuloma development [J]. Acta tropica, 2015, 149: 49-58.

[13] WANG Z, FAYNGERTS S, WANG P, et al. TIPE2 protein serves as a negative regulator of phagocytosis and oxidative burst during infection [J]. Proceedings of the National Academy of Sciences, 2012, 109(38): 15413-8.

[14] WANG Z, QIU J, GUO T B, et al. Anti-Inflammatory Properties and Regulatory Mechanism of a Novel Derivative of Artemisinin in Experimental Autoimmune Encephalomyelitis [J]. The Journal of Immunology, 2007, 179(9): 5958-65.

[15] HU W, YAN Q, SHEN D-K, et al. Evolutionary and biomedical implications of a Schistosoma japonicum complementary DNA resource [J]. Nature genetics, 2003, 35(2): 139-47.