Ke Jiang, Ph.D.
Postdoc (Heeschen Lab)
Email: jiangke.3@163.com
Office: Room 401, East 5 building
Jiang graduated in Veterinary Medicine at the Hunan Agricultural University. He holds an M.Sc. in Preventive Veterinary Medicine from Yangzhou University. Jiang obtained his Ph.D. in Biochemistry and Molecular Biology at the Institute of Cancer Stem Cells, Dalian Medical University, for his studies on SASH1 in triple negative breast cancer. He showed that SASH1 suppresses cell invasion via the YAP-ARHGAP42-actin axis. In September 2020 he joined the Stem Cell & Cancer Lab at the Center for Single Cell Omics. He is developing novel CAR T-cell-based immunotherapies for pancreatic cancer using syngeneic mouse models.
Publications:
1. Ke Jiang, Peng Liu, Huizhe Xu, Dapeng Liang, Kun Fang, Sha Du, Wei Cheng, Leiguang Ye, Tong Liu, Xiaohong Zhang, Peng Gong, Shujuan Shao, Yifei Wang, Songshu Meng, SASH1 suppresses triple negative breast cancer cell invasion through YAP-ARHGAP42-actin axis. Oncogene. 2020 Jul;39(27): 5015-5030.（IF=8.0）
2. Ke Jiang, Gang Yao, Lulu Hu, Jia Liu, Ji Shi, Youwei Chang, Ye Zhang, Dapeng Liang, Dachuan Shen, Guirong Zhang, Yumei Yan, Songshu Meng, Haozhe Piao. MOB2 suppresses GBM cell migration and invasion via regulation of FAK/Akt and cAMP/PKA signaling. Cell death and disease. 2020 Apr 15;11:230. (IF=6.3）
3. Ke Jiang, Cuiping Song, Lingkai Kong, Lulu Hu, Guibin Lin, Tian Ye, Gang Yao, Yupeng Wang, Haibo Chen, Wei Cheng, Martin P. Barr, Quentin Liu, Guirong Zhang, Chan Ding, Songshu Meng. Recombinant oncolytic Newcastle disease virus displays antitumor activities in anaplastic thyroid cancer cells. BMC Cancer. 2018 Jul 18;18(1):746.（IF=3.3）
4. Tian Ye, Ke Jiang, Liwen Wei, Martin P Barr, Qing Xu, Guirong Zhang, Chan Ding, Songshu Meng, and Haozhe Piao. Oncolytic Newcastle disease virus induces autophagy-dependent immunogenic cell death in lung cancer cells. Am J Cancer Res. 2018 Aug 1;8(8):1514-1527 (Co-first author, IF=5.2)
5. Zhen Li, Ke Jiang, Xiaofang Zhu, Guibin Lin, Fei Song, Yongjun Piao, Jiwei Liu, Wei Cheng, Xiaolin Bi, Peng Gong, Zhiqi Song, Songshu Meng. Encorafenib (LGX818), a potent BRAF inhibitor, induces senescence accompanied by autophagy in BRAFV600E melanoma cells. Cancer Letters. 2016 Jan 28; 370 (2): 332-44. (Co-first author, IF=6.4)
